Angiosarcoma can arise in any soft tissue structure. About half of patients present with a primary cutaneous lesion. Risk factors include prior radiation exposure as well as inflammatory damage in chronically sun exposed skin. click this link here nowAngiosarcoma has also been associated with chronic lymphedema. Although resection with curative intent followed by adjuvant radiotherapy is the treatment of choice for localized disease amenable to surgery, approximately 50% of these patients will develop metastases and die from the disease. Furthermore, metastases are frequently present at diagnosis, and resection of metastases is rarely feasible. Read More Angiosarcoma is an extremely rare disease and meets the definition for an orphan disease in the US and European Union (EU), the two regions for which the Phase 3 TAPPAS study is planned. TRC105 has received orphan designation for the treatment of soft tissue sarcoma in both the US and EU. The annual incidence of angiosarcoma in the US was reported by the NCI in 2015 to be 475 cases. In the EU the incidence of angiosarcoma is 0.01 per 10,000, accounting for an estimated 508 cases annually. About TRACON TRACON develops targeted therapies for cancer, ophthalmic and fibrotic diseases. Read Full ReportThe Companys clinical-stage pipeline includes: TRC105, an endoglin antibody that is being developed for the treatment of multiple cancers; DE-122, the ophthalmic formulation of TRC105 that is being developed in wet AMD through a collaboration with Santen Pharmaceutical Company Ltd.; and TRC102, a small molecule that is being developed for the treatment of lung cancer and glioblastoma. The Company is also developing two programs in-licensed from Janssen Pharmaceutica N.V.
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Yet that didnt stop the Fox News Channel from distributing choice excerpts from the pairs conversation late Monday night. After all, the two antagonists turned besties spent a good chunk of it discussing President-elect Donald Trumps favorite subject to forget Russias alleged hacking of the election he won. According to The Hill, Assange charged President Barack Obama and his outgoing staff with trying to delegitimize the Trump administration as it goes into the White House. While reiterating the claim that the Obama administration wants Americans to think President-elect Trump is not a legitimate president, Assange went on the defensive when Hannity asked whether or not Russia was the source of Wikileaks hacked documents. Our source is not a state party, he argued , so the answer for our interactions is no: Our publications had wide uptake by the American people, theyre all true, Assange continued. But thats not the allegation thats being presented by the Obama White House. Aside from the focus on Russia and whether or not Trumps election victory was legitimate, Assange and Hannity also discussed the prevalence of Wikileaks involvement in the 2016 presidential race. The former was especially amused when the Fox News personality asked whether or not he thought his organization had affected the outcome of the election. Who knows, its impossible to tell, said Assange, adding: But if it did, the accusation is that the true statements of Hillary Clinton and her campaign manager, John Podesta, and the DNC head Debbie Wasserman Schultz, their true statements is what changed the election. The new interview will air during a special edition of Hannity at 10 p.m. ET on the Fox News Channel.
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